There is 2 camps on this topic. Some feel it is ok to use drill bits and some dont. I would not just for cleaning as the flutes will start removing metal. I also wouldn't either as jets are designed to work as a venturi. If you drill them out, that effect is gone. best thing for cleaning the jets out is just to use a thin strand of copper wire or a carb cleaning tool shown on this page. It is #9. It will clean virtually any jet.
home.earthlink.net/~motorstuff/tools02.html
The ride IS the adventure. The destination is just to get gas!