OK what bike is this? cb750 in 76 was either a K or an F also called a supersport.
Either way the tires should be fine if you get a 100/90-19 front and 120/90-18(?) rear. I think the 76 had an 18 inch rear rim.
The jets are hard to say. There is no perfect size. I guess the kerker is a 4-1. I would say to start about 120 mains and maybe up 5 on the idle jets. from there, do a plug chop at various rpm and see what your plugs look like.
The ride IS the adventure. The destination is just to get gas!