We'll need a little more detail: what year, is there oil, has it been changed lately, have you done any maintenance to it since you got it, chains tensioned, valves adjusted, carbs worked on/synchronized...
You said high rpm running...are we talking at or near redline? in all gears or just low or high ones?
Usually it's an oil supply issue, or lack of it, to a bearing or somesuch. That's a first guess. I'm sure others with better knowledge will chime in.
Luke M
Used to have a 1979 CB750L, sold it as a parts bike, now riding a slightly modified 1984 VT700C. Network/Field Engineer. Central OH, USA, Earth, Sol System, Milky Way Galaxy, Universe.